产品货号:
Z14705
中文名称:
DAPK2抗体
英文名称:
Anti-DAPK2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DAPK2 Antibody |
指标别名 | DAP kinase 2;DAP kinase related protein 1;DAPK2;DAPK2-Specific;DRP 1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | DAPK2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | DAPK2 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human DAPK2.This antigenic peptide is identical to the corresponding amino acids of mouse origin (1,2).The immunogen is located within the last 50 amino acids of DAPK2. |
计算分子量 | 43kDa |
成分 | DAPK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | DAPK2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases,such as RIP and DAP kinase,are mediators of apoptosis.DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain.Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation.DAPK mediates IFN污induced apoptosis.A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1.Ectopicly expressed DAPK2 induced apoptosis in various types of cells.DAPK has high sequence homology to ZIP kinase and DRAK1/2,and they represent a novel family of serine/threonine kinases,which mediates apoptosis through their catalytic activities.The messenger RNA of DAPK2 is expressed in multiple human tissues. |
Uniprot ID | Q9UIK4 |
基因名全称 | Death-associated protein kinase 2 |
蛋白名全称 | Death-associated protein kinase 2 |
推荐稀释比 | DAPK2 antibody can be used for detection of DAPK2 by Western blot at 1μg/mL.An approximately 42kDa band can be detected.DAPK2 has no cross responses to DAPK1.Antibody can also be used for immunohistochemistry starting at 2μg/mL.Antibody validated:Western Blot in human,mouse,and rat samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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